Does tadalafil cause back pain?

Back pain and/or myalgia (the two may overlap)  are seen with all PDE5 inhibitors, but  Supplement  Vol. 2, No. 1, pp. 141–157, March 2005 151  are reported more frequently with tadalafil.  Generally, about 5% of men taking tadalafil  will experience back pain, which may occur 12  to 24 hours after dose administration, and  typically resolves within 48 hours [21,22]. For  the men who are troubled by this symptom, an  over the counter analgesic such as acetaminophen  can be taken for relief. Only about 0.5% of  men taking tadalafil (less than 1 in 100) found  the back pain sufficiently problematic that  drug discontinuation occurred. Most importantly,  prospective evaluation of patients  experiencing back pain or myalgia did not  reveal any evidence of an inflammation, rhabdomyolysis,  or renal abnormality.