No. Tmax is the time to peak plasma concentration and is a pharmacokinetic property of the drug. In contrast, time to onset of action is a pharamcodynamic measurement assessed clinically (i.e., the elapsed time between taking a pill and achieving the desired clinical effect – in this case, an erection). Because Tmax predicts the time to maximum plasma concentration, clinicians sometimes mistakenly equate it with the time to onset of efficacy. However, maximum plasma concentrations are typically not required for efficacy. Consequently, the time required to reach efficacious plasma levels is usually shorter than the time required to achieve peak plasma levels.
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