The half-life of tadalafil is 17.5 hours. For comparison, the half-lives of other commonly used drugs in primary practice include 14 hours for atorvastatin (Lipitor1), about 15 hours for tamsulosin (Flomax1), 15 hours for naproxen sodium (Anaprox1), about 22 hours for doxazosin (Cardura1), 24 to 26 hours for sertraline (Zoloft1), and 5 weeks for dutasteride (Avodart1).
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